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Year : 2022  |  Volume : 9  |  Issue : 2  |  Page : 77-81

SARS-CoV-2 infection-related acute parkinsonism and encephalitis: Is there a clinicoradiological correlation?

Department of Neurology, Gleneagles Global Health City, Chennai, Tamil Nadu, India

Correspondence Address:
Vikash Agarwal
4C, BBCL Ananya, 17/34 Five Furlong Road, Guindy, Chennai - 600 032, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jnbs.jnbs_45_21

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COVID-19 infection can cause neurological manifestations as early and late complications (chronic COVID syndrome). These include headache, dizziness, confusion, acute cerebrovascular problems, ataxia, and seizures. COVID-19-related encephalopathy, encephalitis, and parkinsonism have been reported earlier; however, the possible links and pathophysiological mechanisms are unclear. In this report, we report a series of patients (n = 5) presenting with acute severe neurological syndromes such as parkinsonism, focal status epilepticus, or acute ataxia as a part of long-hauler COVID-19 infection. We categorized the clinico-radiological and electroencephalographic features in our cases to understand the clinical patterns in SARS-CoV-2 related brain cortex involvement. This might help in future for better clinical categorization for these COVID-19-related neurological manifestations.

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