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ORIGINAL ARTICLE
Year : 2020  |  Volume : 7  |  Issue : 3  |  Page : 152-155

The Distribution of Brain-Derived Neurotrophic Factor rs6265 Polymorphism in Turkish Volleyball Players


1 Marmara University, Faculty of Dentistry, Basic Medical Sciences, Medical Biology and Genetics Department, Istanbul, Turkey
2 Uskudar University of Medical Genetics and Molecular Diagnostic Laboratory, Istanbul, Turkey
3 Pamukkale University, Faculty of Sports Science, Sports Management Department, Denizli, Turkey
4 Marmara University, Faculty of Dentistry, Basic Medical Sciences, Medical Biology and Genetics Department; Uskudar University of Medical Genetics and Molecular Diagnostic Laboratory, Istanbul, Turkey

Correspondence Address:
Korkut Ulucan
Marmara University, Faculty of Dentistry, Basic Medical Sciences, Medical Biology and Genetics Department; Uskudar University of Medical Genetics and Molecular Diagnostic Laboratory, Istanbul, Turkey
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jnbs.jnbs_28_20

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Athletic performance is associated with many environmental factors such as inborn genetic factors, nutrition, psychological factors, and education. We aimed to analyze the brain-derived neurotrophic factor (BDNF) rs6265 polymorphism, which is an important genetic marker related to psychological factors, in 21 professional female volleyball players and compare it with the control group. Genotyping was assessed by real-time polymerase chain reaction technique. BDNF rs6265 polymorphism genotypes were calculated as 72% and 28% for GG and GA in volleyball players, respectively. No AA genotype was detected. In the control group, the GG, GA, and AA genotype percentages were calculated as 57.8, 36.3, and 5.9, respectively. In the allelic distribution, the percentages in the athlete group were calculated as 86% (36) for the G allele and 14% (6) for the A allele, respectively. In the control group, for the G and A alleles, respectively, it was 76.25% and 23.75%. No statistical significance was found in terms of both genotype distribution (P = 0.407) and allelic frequency distribution (P = 0.218). Our results were in line with data indicating the stress and anxiety-related nature of professional volleyball players. More studies with more athletes and more groups of athletes are needed to understand the effect of these parameters on volleyball players.


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